Reassessing Medical Risk in Living Kidney Donors

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Reassessing medical risk in living kidney donors.

The short- and long-term effects of unilateral nephrectomy on living donors have been important considerations for 60 years. Short-term risk is well established (0.03% mortality and <1% risk of major morbidity), but characterization of long-term risk is evolving. Relative to the general population, risk of mortality, ESRD, hypertension, proteinuria, and cardiovascular disease is comparable or l...

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Acute dialysis risk in living kidney donors

BACKGROUND Reduced kidney function confers a higher risk of acute kidney injury at the time of an inciting event, such as sepsis. Whether the same is true in those with reduced renal mass from living kidney donation is unknown. METHODS We conducted a population-based matched cohort study of all living kidney donors in the province of Ontario, Canada who underwent donor nephrectomy from 1992 t...

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Evaluation of high-risk living kidney donors.

Careful evaluation of potential living kidney donors is crucial to assure the well being of the donors, especially because they do not gain any direct medical benefit from donation. This process also helps assess the quality and safety of the organs donated to the recipients. While all programs share these goals, donor selection criteria vary significantly among U.S. transplant centers. In part...

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Racial variation in medical outcomes among living kidney donors.

BACKGROUND Data regarding health outcomes among living kidney donors are lacking, especially among nonwhite persons. METHODS We linked identifiers from the Organ Procurement and Transplantation Network (OPTN) with administrative data of a private U.S. health insurer and performed a retrospective study of 4650 persons who had been living kidney donors from October 1987 through July 2007 and wh...

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Meta-analysis: risk for hypertension in living kidney donors.

BACKGROUND The risk for hypertension after kidney donation remains uncertain. PURPOSE To see whether normotensive adults who donate a kidney develop higher blood pressure and risk for hypertension compared with nondonor adults acting as control participants. DATA SOURCES MEDLINE, EMBASE, and Science Citation Index were searched from 1966 until November 2005 for articles published in any lan...

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ژورنال

عنوان ژورنال: Journal of the American Society of Nephrology

سال: 2014

ISSN: 1046-6673,1533-3450

DOI: 10.1681/asn.2014030227